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omega-3 informations
Omega-3 and health
Omega-3 and women
· Menopause
 
The menopause is a natural phenomenon defined by the stopping of a woman's periods. Physiologically, it corresponds to the stopping of a woman's secretion of reproductive hormones: oestrogen and progesterone.
 
The menopause, however, does not occur all in one day. It is preceded by warning signs that appear when a woman is aged around 45: irregular periods and hot flushes.
 
These hormonal disturbances can lead to the emergence of major medical conditions (cardiovascular disease and osteoporosis) as well as menopausal disorders, known as climacteric disorders (hot flushes, vaginal disorders, sleep disorders, mood disorders, fatigue...)
 
Not all women's experience of the menopause is the same, but in more than 75% of women (source: the French Association for Menopause "AFEM"), the most common symptom of the menopause - and the most difficult to live with - is hot flushes.

Hot flushes can be tolerable and infrequent but they can also, on the other hand, be powerful and occur up to 20 times per day. A sudden feeling of warmth pervades the face, neck, scalp, and even the whole body, usually for 1 to 2 minutes, and the sensation is unstoppable... The skin may become red and perspire profusely. Hot flushes usually last for several years and can occur at any time, making them very bothersome.

Hot flushes are frequently accompanied by particularly unpleasant night-time perspiring.
 
 
Where do the hot flushes come from?

Following the cessation of oestrogen production by the ovaries, the body's thermoregulatory system is unsettled. A disturbance in exchanges between the hypothalamus (which regulates body temperature) and some neurotransmitters such as serotonin and norepinephrine is likely.
 
isodisnatura has collaborated with the Faculty of Medicine at Quebec's Laval University on a clinical study to measure the effectiveness of OM3menopause in the treatment of hot flushes in menopausal women.
 
This revolutionary study has confirmed, for the first time, the benefits of EPA in reducing hot flushes. Indeed, EPA, in its synthesis of the various neurotransmitters that control emotional symptoms, allows for the standardisation of the thermoregulation process.
 
OM3menopause has demonstrated its effectiveness in a clinical study in which 91 women participated (a double-blind placebo-controlled randomised study). In fact, this innovative formulation guarantees you 55% fewer hot flushes after just 8 weeks of treatment.
 
 
Study ref.: Lucas M. et al. ‘Ethyl-eicosapentaenoic acid for the treatment of psychological distress and depressive symptoms in middle-aged women: a double-blind, placebo-controlled, randomized clinical trial' Am J Clin Nutr 2009; 89:641–651


Now, for the first time, isodisnatura is offering you a soy-free, hormone-free product to help you reduce your hot flushes: go to the OM3menopause technical datasheet.

Moreover, the natural protection provided by oestrogens tends to decline during the menopause: cholesterol and triglyceride levels in the blood increase, thus heightening the risk of cardiovascular disease. A recent study (Nagourney et al, 2004) shows that depressive symptoms, even moderate, expose post-menopausal women to an increased risk of cardiovascular disease. This cardiovascular risk can be reduced by the intake of polyunsaturated fatty acids.
 
Finally, symptoms of depression are present in 10 to 40% of menopausal women (Avis, Brambilla et al. 1994; Burt, Altshuler et al. 1998; Dennerstein, Dudley et al. 2000).

 
· Pregnancy and lactation

We know that omega-3 acids are essential for the development of the nervous system in the fœtus and infant, and that women who take little omega-3 during pregnancy have a higher risk of post-natal depression.

Two Danish studies have shown that women who take additional omega-3 acids in the last three months of pregnancy have children with healthier birth rates and are less likely to give birth prematurely. A panel of experts headed by the American nutritionist Artemis Simopoulos, a specialist in omega-3 acids, has made the recommendation that pregnant women take 300mg of omega-3 acids per day during the last three months of pregnancy, and also while breast-feeding, to ensure the infant is properly nourished and to replace the mother's reserves.
 
With a positive impact on health overall, an adequate intake of omega3 is very important during pregnancy (Freeman MP et al, 2004), to prevent a whole range of maternal and infantile complications.
 The fatty-acid composition of the amniotic fluid and mother's milk is very much dependent on the mother's diet.  A pregnant woman has her own reserves of omega3, but these are not always sufficient. Indeed, reserves of polyunsaturated fatty acids are constituted well before pregnancy, and so depend on the lifestyle of the future mother. A woman should therefore make sure her omega-3 intake is sufficient as soon as she decides to conceive a child, and throughout pregnancy.
The mother's omega3 is transferred to the fœtus during pregnancy, with a potential depletion for the mother (Min Y et al, 2000). Many studies have shown that pregnant women who eat a lot of fish, or who take omega-3 supplements, have fewer complications than others: this intake seems to provide protection from premature birth, pre-eclampsia (Williams MA et al, 1995), and cerebral palsy (Petridou et al, 1998).
It is also important to note that a study has demonstrated the absence of undesirable effects for the fœtus and for the progression of pregnancy and birth (Olsen SF et al, 1992) with regard to omega-3 intake during pregnancy. 
DHA plays a crucial role in a successful pregnancy; it is essential for brain growth and development of the foetus.
DHA, also called cervonic acid, acts on vision (particularly the retina), neuronal functions (cognitive) and chemical messages of the brain (Holman RT et al, 1991).
Omega-3 is also associated with the prevention of weight problems and high blood pressure among children of women who take most omega3. At fifteen months, the babies of these women also show a better psychomotor development than others.
 
· Menstruation
 
In a Danish study, women who received additional omega-3 acids (with oral vitamin B12) had less painful menstrual cycles (Deutch 1995; Deutch, Jorgensen et al. 2000).

 
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